Borna disease in a dog with lethal meningoencephalitis.
نویسندگان
چکیده
A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
منابع مشابه
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 36 7 شماره
صفحات -
تاریخ انتشار 1998